[LA-SiGMA] LI-LA-SiGMA seminar Today, April 26

[Dentcho Genov]

Dear All,

 

This is a kind reminder that our next LI-LA-SiGMA seminar is today, April 26
at 2.00pm. Our speaker is Dr. Jake Chen, Indiana University - Purdue
University Indianapolis (IUPUI)

 

Title: 3D+ X-ray & Neutron Imaging in Materials Science for Energy: Hydrogen
Storage and Batteries

 

Abstract:  Today, the default model for small molecule drug discovery is to
screen libraries of chemical compounds against a single protein drug target
determined to be critical to a disease. The process is long, costly,
serendipitous, and infested with failures. New evidence from emerging genome
biology studies suggests that complex diseases may never be addressed by
simple "one disease one target" or "target-compound docking" models. New
translational medicine approaches are needed to save future pharmaceutical
industry from crumbling.

In this talk, I describe how advances in translational bioinformatics are
making it possible to begin approaching such drug discovery challenges with
new computational ideas. I will introduce the concept of connectivity maps,
and then describe how bioinformatics techniques can be developed to study
the complex relationships among diseases, genes, and drugs. I will show how
converging techniques, software tools, and databases are being developed in
our research program at the Indiana Center for Systems Biology and
Personalized Medicine and my lab ( <http://bio.informatics.iupui.edu/>
http://bio.informatics.iupui.edu/) to achieve progress towards a new
paradigm of computational drug discovery.

 

Bio: Dr. Jake Chen is an associate professor with tenure at Indiana
University School of Informatics and Purdue University Department of
Computer and Information Science in Indianapolis (IUPUI). He is the founding
director of the Indiana Center for Systems Biology and Personalized
Medicine, a member of the Indiana University Simon Cancer Center, and a
member of the Center for Computational Biology and Bioinformatics at Indiana
University School of Medicine. He is also an ACM senior member, IEEE senior
member, and chair of the IEEE Engineering in Biology and Medicine Society
Central Indiana Chapter. He currently serves on the editorial boards of
several international bioinformatics journals including BMC Systems Biology,
organized over 100 Academic meetings in informatics and computer science,
and served on many research panels or committees for NIH, NSF, DOE, and the
National Academies. He is the recipient of the Canary Foundation 2008
Bioinformatics Dissemination Award, a Translational Research into Practice
(TRIP) scholar at Indiana University, and a 2010 Cambridge Health
Institute's Translational Medicine Conference Distinguished Faculty. He
holds masters and doctoral degrees in Computer Science & Engineering from
the University of Minnesota and a bachelor degree in Biochemistry &
Molecular Biology from Peking University of China.

His research expertise spans over biological data management, biological
data mining, bioinformatics, systems biology, and clinical applications of
genomics in predictive and personalized medicine, with more than 90 research
publication-including three edited books, Biological Database Modeling,
Biological Data Mining, and Translational Bioinformatics (forthcoming)-and
more than 100 invited talks worldwide. 

He also has considerable experience in leading Informatics R&D projects in
the biopharmaceutical industry. Prior to joining Academia in 2004, he helped
design commercial GeneChip microarray products for human, mouse, and rat at
Affymetrix, Inc., San Jose, California and led a team to data mine the
world's first comprehensive human protein interactome collected at Myriad
Proteomics, Inc., Salt Lake City, Utah. In Indiana, he co-founded the
non-profit Indiana Biomedical Entrepreneur's Network (IBEN) to promote
biotechnology commercialization efforts and two biotech startup businesses
to promote predictive and personalized medicine practices. 

 

The access grid locations are as follow: 

 

Tulane: AG room: 403 Stanley Thomas Hall

University of Louisiana at Lafayette: AG room: Abdalla Hall

Southern University:  AG room: 218 Moore Hall

UNO: AG room:  SC 2002

LSU: AG room:  Johnston 338

LATECH: AG room: 234 Netken Hall

 

Please, distribute this email to your students and colleagues.

 

Kind Regards,

Dentcho

 

----

Dentcho A. Genov, PhD

The LONI Institute Fellow

Assistant Professor of Physics & Electrical Engineering

Louisiana Tech University, Engineering Annex, Room 220

599 W Arizona Ave, Ruston LA 71272

 

Phone: (318) 257-4190, Fax: (318) 257-2777

Webpage: http://www.phys.latech.edu/~dgenov/

 

 

 

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